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Warming Up to Cold Perfusion

List of authors.
  • Winfred W. Williams, M.D.,
  • and James F. Markmann, M.D., Ph.D.

Each year, thousands of people in the United States die while awaiting lifesaving liver transplantation because there is an insufficient supply of donor organs. This crisis has prompted increased interest in expanding the organ supply through the promotion of both deceased and live liver donation and has led to the encouragement of use of organs from so-called expanded-criteria donation grafts from older donors, grafts with suboptimal organ quality (e.g., with varying degrees of fatty liver deposits or steatosis), or grafts that had sustained prolonged ischemia times after they were obtained. Livers from deceased donors that are obtained after circulatory . . .

Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this editorial at

This editorial was published on February 24, 2021, at

Author Affiliations

From the Division of Transplant Surgery and Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston (J.F.M.).