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Acute Severe Hypertension

List of authors.
  • Aldo J. Peixoto, M.D.

Acute severe hypertension accompanied by acute target-organ injury (hypertensive emergency) requires immediate treatment with IV antihypertensive agents (based on the type of target-organ damage) in an ICU. In the absence of target-organ injury, treatment involves oral medication in the ambulatory setting.

Funding and Disclosures

Disclosure forms provided by the author are available with the full text of this article at NEJM.org.

Dr. Peixoto reports receiving grant support, paid to Yale University, from Vascular Dynamics, Bayer, Lundbeck, Otsuka, Allena Pharmaceuticals, and Boehringer Ingelheim, fees for serving on a data and safety monitoring board from Ablative Solutions, and advisory board fees from Relypsa and DiaMedica Therapeutics. No other potential conflict of interest relevant to this article was reported.

Author Affiliations

From the Department of Internal Medicine, Section of Nephrology, Yale School of Medicine, and the Hypertension Program, Yale New Haven Hospital Heart and Vascular Center, New Haven, CT.

Address reprint requests to Dr. Peixoto at Boardman 114 (Nephrology), 330 Cedar St., New Haven, CT 06520, or at .

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