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Clinical PracticeFree Preview

Immune Thrombocytopenia

List of authors.
  • Nichola Cooper, M.D., M.B., B.S.,
  • and Waleed Ghanima, M.B., Ch.B., Ph.D.

Immune thrombocytopenia in patients who present with serious bleeding is treated with platelet transfusions, glucocorticoids, and intravenous immune globulin. In patients without serious bleeding, treatment decisions are guided by the platelet count and other factors. Commonly used agents include glucocorticoids, thrombopoietin-receptor agonists, and rituximab.

Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Dr. Cooper reports receiving fees paid to her institution for serving as a principal investigator for clinical trials, advisory board fees, and lecture fees from Amgen and Novartis, fees paid to her institution for serving as a principal investigator and co-investigator for clinical trials and honoraria from Rigel Pharmaceuticals, fees paid to her institution for serving as a principal investigator for clinical trials from Protalex, and fees paid to her institution for serving as a principal investigator for clinical trials and for serving on an advisory board from Principa; and Dr. Ghanima, receiving advisory board fees and lecture fees from Amgen and grant support paid to his institution, advisory board fees, and lecture fees from Novartis. No other potential conflict of interest relevant to this article was reported.

This article was updated on September 6, 2019, at NEJM.org.

Author Affiliations

From the Department of Medicine, Hammersmith Hospital, Imperial College, London (N.C.); and the Departments of Medicine, HematologyCOncology, and Research, ?stfold Hospital Trust, Kalnes, and the Department of Hematology, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo (W.G.) both in Norway.

Address reprint requests to Dr. Cooper at the Department of Medicine, Hammersmith Hospital, Imperial College, Du Cane Rd., London W12 0HS, United Kingdom, or at .

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