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Hormone Therapy for Postmenopausal Women

List of authors.
  • JoAnn V. Pinkerton, M.D.

Hormone therapy is highly effective for the management of vasomotor symptoms in postmenopausal women; vaginal estrogen is used for genitourinary symptoms only. Hormone therapy is not recommended for primary or secondary prevention of coronary heart disease or dementia. Several nonhormonal therapies are also effective for vasomotor symptoms.

Funding and Disclosures

Disclosure forms provided by the author are available with the full text of this article at NEJM.org.

Dr. Pinkerton reports receiving grant support, paid to the University of Virginia, from TherapeuticsMD. No other potential conflict of interest relevant to this article was reported.

I thank JoAnn E. Manson, M.D., Dr.P.H, Brigham and Womens Hospital and Harvard Medical School, Boston, and others for their expert review of an earlier version of this manuscript; Katherine Pettitt for information design; and Marisa Vacca for administrative assistance.

Author Affiliations

From the University of Virginia Health System, Charlottesville.

Address reprint requests to Dr. Pinkerton at the University of Virginia Health System, Box 8041014, Charlottesville, VA 22908-1104, or at .

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