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Case Records of the Massachusetts General HospitalFree Preview

Case 6-2021: A 65-Year-Old Man with Eye Pain and Decreased Vision

List of authors.
  • Marc A. Bouffard, M.D.,
  • Bart K. Chwalisz, M.D.,
  • Javier M. Romero, M.D.,
  • Isabel C. Arrillaga-Romany, M.D.,
  • and Lucas R. Massoth, M.D.

A 65-year-old man with Waldenstr?ms macroglobulinemia was evaluated because of an 8-day history of bilateral eye pain and decreased vision. He had decreased visual acuity, dyschromatopsia, visual field loss, a relative afferent pupillary defect, and an abnormal appearance of the optic disk. A diagnosis was made.

Funding and Disclosures

This case was presented at Neurology Grand Rounds.

Disclosure forms provided by the authors are available at

We thank Drs. Lawrence R. Zukerberg and Mandakolathur R. Murali for assistance with the pathological discussion.

Author Affiliations

From the Department of Neurology, Beth Israel Deaconess Medical Center (M.A.B.), the Departments of Neurology (B.K.C.), Radiology (J.M.R.), Neuro-oncology (I.C.A.-R.), and Pathology (L.R.M.), Massachusetts General Hospital, and the Departments of Neurology (B.K.C.), Radiology (J.M.R.), Neuro-oncology (I.C.A.-R.), and Pathology (L.R.M.), Harvard Medical School all in Boston.

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