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Case Records of the Massachusetts General HospitalFree Preview

Case 3-2021: A 48-Year-Old Man with Transient Vision Loss

List of authors.
  • Sebastian H. Unizony, M.D.,
  • Hillary R. Kelly, M.D.,
  • Elizabeth K. O¡¯Donnell, M.D.,
  • and Sam Sadigh, M.D.

A 48-year-old man presented with acute vision loss that lasted 1 hour. His history included fatigue and weight loss of 4.5 kg in the past year, as well as bilateral jaw pain with chewing in the past 2 months. He had normocytic anemia and elevated levels of aminotransferases and alkaline phosphatase. A diagnostic test was performed.

Funding and Disclosures

This case was presented at the Medicine Case Conference.

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Dr. Unizony reports receiving consulting fees from Kiniksa and Janssen and research support from Genentech; Dr. Kelly, receiving clinical trial funding, paid to her institution, from Bayer; and Dr. O¡¯Donnell, receiving clinical trial funding, paid to her institution, consulting fees, and honoraria from Janssen and Bristol Myers Squibb, clinical trial funding, paid to her institution, from Amgen, clinical trial funding, paid to her institution, and honoraria from Takeda, and honoraria from Karyopharm and Oncopeptides. No other potential conflict of interest relevant to this article was reported.

Author Affiliations

From the Departments of Medicine (S.H.U., E.K.O.), Radiology (H.R.K.), and Pathology (S.S.), Massachusetts General Hospital, the Departments of Medicine (S.H.U., E.K.O.), Radiology (H.R.K.), and Pathology (S.S.), Harvard Medical School, and the Department of Radiology, Massachusetts Eye and Ear (H.R.K.) ¡ª all in Boston.

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