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Clinical PracticeFree Preview

Native-Valve Infective Endocarditis

List of authors.
  • Henry F. Chambers, M.D.,
  • and Arnold S. Bayer, M.D.

The diagnosis of infectious endocarditis is based on modified Duke criteria, according to findings on physical examination, echocardiography, microbiologic studies, and imaging of target organs. The selection and duration of antibiotic treatment depend on culture results. Early surgery is indicated in some patients.

Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

No potential conflict of interest relevant to this article was reported.

Author Affiliations

From the Division of HIV, Infectious Diseases, and Global Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco (H.F.C.); and the Division of Infectious Diseases, HarborCUCLA (University of California, Los Angeles) Medical Center, and the David Geffen School of Medicine at UCLA, Los Angeles, and the Lundquist Institute, Torrance both in California (A.S.B.).

Address reprint requests to Dr. Chambers at the Division of HIV, Infectious Diseases, and Global Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco, 1001 Potrero Ave., San Francisco, CA 94110, or at .

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