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Clinical PracticeFree Preview

Care of Transgender Persons

List of authors.
  • Joshua D. Safer, M.D.,
  • and Vin Tangpricha, M.D., Ph.D.

Approximately 0.6% of the U.S. population identifies as transgender. Depending on patient preference, treatment may involve hormone therapy (testosterone in transgender men, estrogens and androgen-lowering agents in transgender women), surgery customized to patient goals, and fertility preservation.

Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Dr. Safer reports receiving fees for serving on an advisory board from Endo Pharmaceuticals. No other potential conflict of interest relevant to this article was reported.

We thank John H. Pang, MD, Mount Sinai Health System, for his assistance in reviewing the figure.

Author Affiliations

From the Center for Transgender Medicine and Surgery, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York (J.D.S.); and the Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, and the Atlanta Veterans Affairs Medical Center both in Atlanta (V.T.).

Address reprint requests to Dr. Safer at the Center for Transgender Medicine and Surgery, Rm. D-240, Center for Advanced Medicine, 17 E. 102nd St., New York, NY 10029, or at .

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