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Secondary Mitral Regurgitation

List of authors.
  • Patrick T. O¡¯Gara, M.D.,
  • and Michael J. Mack, M.D.

Secondary mitral regurgitation, which results from left ventricular dysfunction or remodeling or atrial disease, is associated with adverse cardiovascular outcomes. Treatment includes guideline-directed medical therapy for heart failure, if present, and in some cases, surgery or transcatheter intervention.

Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Author Affiliations

From the Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women¡¯s Hospital, Harvard Medical School, Boston (P.T.O.); and the Department of Cardiac Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).

Address reprint requests to Dr. O¡¯Gara at the Division of Cardiovascular Medicine, Brigham and Women¡¯s Hospital, 75 Francis St., Boston, MA 02115, or at .

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