The use of e-cigarettes has increased rapidly. Although vaping has been shown to assist with smoking cessation, cases of severe vaping-related pulmonary disease and a number of deaths have recently been reported. Here we present a collection of articles and other resources on e-cigarettes and vaping-related disease, including clinical reports and commentary.

  • Characteristics of EVALI Patients Who Were Rehospitalized or Died after Discharge

    A report and clinical guidance in the Center for Disease Control’s (CDC) Morbidity and Mortality Weekly Reports (MMWR) published on Friday, December 20, emphasize the risk of death or recurrent hospitalization due to e-cigarette, or vaping, product use–associated lung injury (EVALI).

    Among the 1139 patients with EVALI discharged on or before October 31, 2019, 31 (2.7%) were rehospitalized a median of 4 days after discharge and with half of the events occurring between 2 and 20 days after discharge. Seven patients, five of whom were women, died outside the hospital. All patients who died had been in an intensive care unit (ICU) during hospitalization. The deaths occurred a median of 3 days after discharge. The median age of patients who died after discharge was 54 years, as compared with 23 years among patients with no rehospitalizations. Patients with EVALI who required rehospitalization or who died after discharge were more likely to have cardiac disease, chronic obstructive pulmonary disease (COPD), obstructive sleep apnea (OSA), diabetes mellitus, and multiple chronic comorbidities.

    The clinical guidance urges health care professionals to work with appropriate staff to ensure that all patients discharged after treatment for EVALI are reevaluated at 48 hours, especially those who have been in an ICU, have social support networks in place to monitor their health, to ensure that post-discharge medications, such as glucocorticoids on taper and medications for known comorbid conditions, are taken appropriately, and that they do not resume use of vaping or combustible tobacco.

    See the MMWR reports for full details:

    Characteristics of Patients Experiencing Rehospitalization or Death After Hospital Discharge in a Nationwide Outbreak of E-cigarette, or Vaping, Product Use–Associated Lung Injury — United States, 2019

    Update: Interim Guidance for Health Care Professionals Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use–Associated Lung Injury and for Reducing the Risk for Rehospitalization and Death Following Hospital Discharge — United States, December 2019

Additional Articles on E-Cigarettes and Vaping-Related Disease

Lung Injury Associated with Electronic Cigarettes
This interactive graphic tracks lung injury case counts by state, age, sex, and product use. Data and case definition courtesy of the Centers for Disease Control and Prevention.

Guidance for Health Care Providers from the CDC